Prostate cancer- An overview
Cancer is when the cells feature uncontrolled growth. They can grow in any area of the body. Prostate cancer flags off in the prostate gland and could even spread to other body parts and regions. The organ is also responsible for the creation of a part of the fluid which is the portion of the semen.
Prostate gland lies opposite the rectum, underneath the bladder, with its size changing with age – it is bigger in older men but in younger men, the size is like a walnut. Behind it lies the gland known as seminal vesicles which create most of the semen fluid composition. The urethra carries the semen and urine outside the body through the penis; it goes via the center region of the prostate.
Different kinds of prostate cancer
All kinds of prostate cancer are adenocarcinomas. They manifest from the gland cells. The different kinds of cancers include transitional cell carcinomas, neuroendocrine tumors, small cell carcinomas, and Sarcomas. These are rare and if you happen to have prostate cancer, there are high chances of it being an adenocarcinoma. Some types spread quickly while others grow slowly.
Prostate cancer flags off as a pre-cancerous ailment; this is only found in a person who has had a prostate biopsy.
Prostatic intraepithelial neoplasia (PIN) is when the prostate is looked beneath a microscope. Abnormal cells are classified as
- High-grade PIN – a pattern of cells which look abnormal
- Low-grade PIN – a pattern of prostate cells which look almost normal
PIN starts to manifest in the prostate in men in their 20s but may not get prostate cancer.
PIA (Proliferative inflammatory atrophy) is when the prostate cells appear smaller than their normal size, there is also inflammation but it isn’t cancer. It could end up leading to high-grade PIN and then to prostate cancer.
This is the most common form of cancer in men. The research has estimated that in 2019 there will be around 174,650 new cases of prostate cancer and around 31,620 deaths from this cancer. Around one in nine men face risk from this cancer. Around one in six men are over 65 years of age it is a rare case before the age of 40.
Prostate cancer also happens to be the 2 nd leading cause of death in men, close on the heels of lung cancer. It is a serious disease but most men do not die from it.
Risks of prostate cancer
There are risk factors like smoking, age, genetics which cannot be changed. Mostly found in those above the age of 65, age plays an important role.
Geography also plays an important role. It is less common in South America, Central America, Africa and Asia and it most common in Australia, northwestern Europe, and North America.
Family history is a common factor for those whom this disease runs in the family – genetic factor. If you have a brother, father or other male relatives who have this cancer it ups your chances of developing this disease.
Inherited change in the genes increases the risk of developing this cancer. Mutation of BRCA1 or BRCA2 also increases the risk. Men with Lynch syndrome which is caused by inherited gene changes, it has increased the risk of cancer in men.